Comparative analysis of skeletal muscle transcriptional signatures associated with aerobic exercise capacity or response to training in humans and rats

Experiment ID:SRP273786
Technology:RNA-Seq
Description:In this study, we set out to dissect the intrinsic and response components of aerobic exercise at the transcriptional level in the skeletal muscle. Overall design: We employed the selectively bred rat models for divergent intrinsic aerobic capacity, high-capacity runners (HCR) and low-capacity runners (LCR) and for the adaptational aerobic capacity, low response trainers (LRT) and high response trainers (HRT). Using RNA-sequencing, we mapped out the transcriptional profiles of high exercise capacity and high response in skeletal muscle. Lastly, we utilized these signatures to explore molecular mediators of high capacity and response in human volunteers before and after exercise training.
Source:SRP273786  SRA

List of assays

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entries

Library ID
Identifier of the RNA-Seq library
Anat. entity ID
ID of the anatomical localization of the sample
Anat. entity name
Name of the anatomical localization of the sample
Anat. entity author annotation
Free text annotation of anatomical localization of the sample as provided by authors
Stage ID
ID of the developmental and life stage of the sample
Stage name
Name of the developmental and life stage of the sample
Stage author annotation
Free text annotation of the developmental and life stage of the sample as provided by authors
Sex
Annotation of the sex of the sample
Strain
Annotation of the strain of the sample
Time
Free text annotation of the time of sampling as provided by authors
Time unit
Unit for the time of sampling as provided by authors
Species
Physiological status
Physiological status of the organism at time of sampling
Technology
Sequencing platform
Sequenced transcript part
Possible values are: full length, all parts of the transcript are sequenced; 3': only the 3' end of the transcript is sequenced; 5': only the 5' end of the transcript is sequenced.
Fragmentation
Size of the RNA fragmentation
Run sequencing type
Paired-end or single-read run
Total read count
Total number of reads for the library.
Mapped read count
Number of reads that could be mapped to the transcriptome.
Total UMI count
Total number of individual RNA molecules (UMI) for the annotated sample. Only applicable for libraries producing UMIs.
Mapped UMI count
Number of UMIs that could be mapped to the transcriptome. Only applicable for libraries producing UMIs.
Distinct rank count
When performing a fractional ranking of the genes in the annotated sample, based on their expression level, number of distinct ranks observed, to have a value of the power for distinguishing expression levels. Used as a weight to compute a weighted mean rank accross samples for each gene and compute expression scores in Bgee.
Max rank
When performing a fractional ranking of the genes in the annotated sample, based on their expression level, maximum rank attained in the sample. Used to normalize ranks accross samples and compute expression scores in Bgee.
Link to processed expression values
See the processed expression value results for this assay
SRX8833718UBERON:0001388 gastrocnemiusGastrocnemius muscleRnorDv:0000020 4-month-old stage (rat)About 20 weeksNANANANARattus norvegicusNAIlluminaIllumina HiSeq 2500FULL_LENGTH26single4707748337872987001692820757Browse results
SRX8833719UBERON:0001388 gastrocnemiusGastrocnemius muscleRnorDv:0000020 4-month-old stage (rat)About 20 weeksNANANANARattus norvegicusNAIlluminaIllumina HiSeq 2500FULL_LENGTH26single4367179134986435001658420559.5Browse results
SRX8833720UBERON:0001388 gastrocnemiusGastrocnemius muscleRnorDv:0000020 4-month-old stage (rat)About 20 weeksNANANANARattus norvegicusNAIlluminaIllumina HiSeq 2500FULL_LENGTH26single5766094645316492001717320894Browse results
SRX8833721UBERON:0001388 gastrocnemiusGastrocnemius muscleRnorDv:0000020 4-month-old stage (rat)About 20 weeksNANANANARattus norvegicusNAIlluminaIllumina HiSeq 2500FULL_LENGTH26single4717178737299357001656120555Browse results
SRX8833722UBERON:0001388 gastrocnemiusGastrocnemius muscleRnorDv:0000020 4-month-old stage (rat)About 20 weeksNANANANARattus norvegicusNAIlluminaIllumina HiSeq 2500FULL_LENGTH26single4578754336999258001623820412Browse results
SRX8833723UBERON:0001388 gastrocnemiusGastrocnemius muscleRnorDv:0000020 4-month-old stage (rat)About 20 weeksNANANANARattus norvegicusNAIlluminaIllumina HiSeq 2500FULL_LENGTH26single5052904340544929001703320829.5Browse results
SRX8833724UBERON:0001388 gastrocnemiusGastrocnemius muscleRnorDv:0000020 4-month-old stage (rat)About 20 weeksNANANANARattus norvegicusNAIlluminaIllumina HiSeq 2500FULL_LENGTH26single4398515234067448001649720531Browse results
SRX8833725UBERON:0001388 gastrocnemiusGastrocnemius muscleRnorDv:0000020 4-month-old stage (rat)About 20 weeksNANANANARattus norvegicusNAIlluminaIllumina HiSeq 2500FULL_LENGTH26single4674246436042306001676520671.5Browse results
SRX8833726UBERON:0001388 gastrocnemiusGastrocnemius muscleRnorDv:0000020 4-month-old stage (rat)About 20 weeksNANANANARattus norvegicusNAIlluminaIllumina HiSeq 2500FULL_LENGTH26single4807245838212313001632920427.5Browse results
SRX8833727UBERON:0001388 gastrocnemiusGastrocnemius muscleRnorDv:0000020 4-month-old stage (rat)About 20 weeksNANANANARattus norvegicusNAIlluminaIllumina HiSeq 2500FULL_LENGTH26single4635653236692370001683920723.5Browse results
SRX8833728UBERON:0001388 gastrocnemiusGastrocnemius muscleRnorDv:0000020 4-month-old stage (rat)About 20 weeksNANANANARattus norvegicusNAIlluminaIllumina HiSeq 2500FULL_LENGTH26single5136390040928104001662620578Browse results
SRX8833729UBERON:0001388 gastrocnemiusGastrocnemius muscleRnorDv:0000020 4-month-old stage (rat)About 20 weeksNANANANARattus norvegicusNAIlluminaIllumina HiSeq 2500FULL_LENGTH26single4556742036238554001652220546Browse results
SRX8833730UBERON:0001388 gastrocnemiusGastrocnemius muscleRnorDv:0000020 4-month-old stage (rat)About 20 weeksNANANANARattus norvegicusNAIlluminaIllumina HiSeq 2500FULL_LENGTH26single5111625840640747001687520731.5Browse results
SRX8833731UBERON:0001388 gastrocnemiusGastrocnemius muscleRnorDv:0000020 4-month-old stage (rat)About 20 weeksNANANANARattus norvegicusNAIlluminaIllumina HiSeq 2500FULL_LENGTH26single5449349344826107001679420690.5Browse results
SRX8833732UBERON:0001388 gastrocnemiusGastrocnemius muscleRnorDv:0000020 4-month-old stage (rat)About 20 weeksNANANANARattus norvegicusNAIlluminaIllumina HiSeq 2500FULL_LENGTH26single5626545346185512001682920695Browse results
SRX8833733UBERON:0001388 gastrocnemiusGastrocnemius muscleRnorDv:0000020 4-month-old stage (rat)About 20 weeksNANANANARattus norvegicusNAIlluminaIllumina HiSeq 2500FULL_LENGTH26single4478182035606847001640320481.5Browse results
SRX8833734UBERON:0001388 gastrocnemiusGastrocnemius muscleRnorDv:0000020 4-month-old stage (rat)About 20 weeksNANANANARattus norvegicusNAIlluminaIllumina HiSeq 2500FULL_LENGTH26single3399144627330272001619220378Browse results
SRX8833735UBERON:0001388 gastrocnemiusGastrocnemius muscleRnorDv:0000020 4-month-old stage (rat)About 20 weeksNANANANARattus norvegicusNAIlluminaIllumina HiSeq 2500FULL_LENGTH26single5012478038906471001695920789Browse results