Search Genes

Gene : PTGIS - ENSG00000124212 - Homo sapiens (human)

General information

Expressed in parietal pleura and 169 other cell types or tissues.

Gene identifier

ENSG00000124212

Name

PTGIS

Description

prostaglandin I2 synthase [Source:HGNC Symbol;Acc:HGNC:9603]

Organism

Homo sapiens (human)

Synonym(s)

cyp8a1,pgis

Orthologs

41 orthologs

Paralogs

48 paralogs

Source data

Retrieve all processed expression values for that gene

Expression graph

80%

Expression table

80%

Reported absence of expression

80%

Orthologs

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Taxon Name	Species with orthologs	Gene(s)	Expression comparison
Homininae	2 species Pan paniscus (bonobo) Pan troglodytes (chimpanzee)	2 genes ENSPPAG00000042097 PTGIS ENSPTRG00000013608 PTGIS	Compare expression
Catarrhini	8 species Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Chlorocebus sabaeus (Green monkey)	8 genes ENSCATG00000013706 PTGIS ENSMFAG00000033233 PTGIS ENSMMUG00000021692 PTGIS ENSMNEG00000036124 PTGIS ENSPANG00000007535 PTGIS ENSPPAG00000042097 PTGIS ENSPTRG00000013608 PTGIS ENSCSAG00000015010 PTGIS	Compare expression
Simiiformes	9 species Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Chlorocebus sabaeus (Green monkey)	9 genes ENSCJAG00000000578 PTGIS ENSCATG00000013706 PTGIS ENSMFAG00000033233 PTGIS ENSMMUG00000021692 PTGIS ENSMNEG00000036124 PTGIS ENSPANG00000007535 PTGIS ENSPPAG00000042097 PTGIS ENSPTRG00000013608 PTGIS ENSCSAG00000015010 PTGIS	Compare expression
Primates	10 species Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey)	10 genes ENSCJAG00000000578 PTGIS ENSCATG00000013706 PTGIS ENSMFAG00000033233 PTGIS ENSMMUG00000021692 PTGIS ENSMNEG00000036124 PTGIS ENSPANG00000007535 PTGIS ENSPPAG00000042097 PTGIS ENSPTRG00000013608 PTGIS ENSMICG00000017617 PTGIS ENSCSAG00000015010 PTGIS	Compare expression
Euarchontoglires	13 species Mus musculus (mouse) Cavia porcellus (guinea pig) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Rattus norvegicus (rat)	13 genes ENSMUSG00000017969 Ptgis ENSCPOG00000034249 PTGIS ENSCJAG00000000578 PTGIS ENSCATG00000013706 PTGIS ENSMFAG00000033233 PTGIS ENSMMUG00000021692 PTGIS ENSMNEG00000036124 PTGIS ENSPANG00000007535 PTGIS ENSPPAG00000042097 PTGIS ENSPTRG00000013608 PTGIS ENSMICG00000017617 PTGIS ENSCSAG00000015010 PTGIS ENSRNOG00000008245 AABR07054614.1	Compare expression
Boreoeutheria	21 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Cavia porcellus (guinea pig) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat)	21 genes ENSMUSG00000017969 Ptgis ENSCAFG00000011426 PTGIS ENSFCAG00000030511 PTGIS ENSECAG00000016521 PTGIS ENSSSCG00000007463 PTGIS ENSBTAG00000017537 PTGIS ENSCHIG00000011304 PTGIS ENSOARG00000012715 PTGIS ENSCPOG00000034249 PTGIS ENSCJAG00000000578 PTGIS ENSCATG00000013706 PTGIS ENSMFAG00000033233 PTGIS ENSMMUG00000021692 PTGIS ENSMNEG00000036124 PTGIS ENSPANG00000007535 PTGIS ENSPPAG00000042097 PTGIS ENSPTRG00000013608 PTGIS ENSMICG00000017617 PTGIS ENSCSAG00000015010 PTGIS 108391976 PTGIS ENSRNOG00000008245 AABR07054614.1	Compare expression
Theria	22 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Cavia porcellus (guinea pig) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum)	22 genes ENSMUSG00000017969 Ptgis ENSCAFG00000011426 PTGIS ENSFCAG00000030511 PTGIS ENSECAG00000016521 PTGIS ENSSSCG00000007463 PTGIS ENSBTAG00000017537 PTGIS ENSCHIG00000011304 PTGIS ENSOARG00000012715 PTGIS ENSCPOG00000034249 PTGIS ENSCJAG00000000578 PTGIS ENSCATG00000013706 PTGIS ENSMFAG00000033233 PTGIS ENSMMUG00000021692 PTGIS ENSMNEG00000036124 PTGIS ENSPANG00000007535 PTGIS ENSPPAG00000042097 PTGIS ENSPTRG00000013608 PTGIS ENSMICG00000017617 PTGIS ENSCSAG00000015010 PTGIS 108391976 PTGIS ENSRNOG00000008245 AABR07054614.1 ENSMODG00000016298 PTGIS	Compare expression
Mammalia	23 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Cavia porcellus (guinea pig) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum)	23 genes ENSMUSG00000017969 Ptgis ENSCAFG00000011426 PTGIS ENSFCAG00000030511 PTGIS ENSECAG00000016521 PTGIS ENSSSCG00000007463 PTGIS ENSBTAG00000017537 PTGIS ENSCHIG00000011304 PTGIS ENSOARG00000012715 PTGIS ENSCPOG00000034249 PTGIS ENSOANG00000006390 PTGIS ENSCJAG00000000578 PTGIS ENSCATG00000013706 PTGIS ENSMFAG00000033233 PTGIS ENSMMUG00000021692 PTGIS ENSMNEG00000036124 PTGIS ENSPANG00000007535 PTGIS ENSPPAG00000042097 PTGIS ENSPTRG00000013608 PTGIS ENSMICG00000017617 PTGIS ENSCSAG00000015010 PTGIS 108391976 PTGIS ENSRNOG00000008245 AABR07054614.1 ENSMODG00000016298 PTGIS	Compare expression
Amniota	24 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Cavia porcellus (guinea pig) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Anolis carolinensis (green anole)	24 genes ENSMUSG00000017969 Ptgis ENSCAFG00000011426 PTGIS ENSFCAG00000030511 PTGIS ENSECAG00000016521 PTGIS ENSSSCG00000007463 PTGIS ENSBTAG00000017537 PTGIS ENSCHIG00000011304 PTGIS ENSOARG00000012715 PTGIS ENSCPOG00000034249 PTGIS ENSOANG00000006390 PTGIS ENSCJAG00000000578 PTGIS ENSCATG00000013706 PTGIS ENSMFAG00000033233 PTGIS ENSMMUG00000021692 PTGIS ENSMNEG00000036124 PTGIS ENSPANG00000007535 PTGIS ENSPPAG00000042097 PTGIS ENSPTRG00000013608 PTGIS ENSMICG00000017617 PTGIS ENSCSAG00000015010 PTGIS 108391976 PTGIS ENSRNOG00000008245 AABR07054614.1 ENSMODG00000016298 PTGIS ENSACAG00000015827 PTGIS	Compare expression
Tetrapoda	26 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Cavia porcellus (guinea pig) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Xenopus laevis (African clawed frog) Xenopus tropicalis (western clawed frog) Anolis carolinensis (green anole)	26 genes ENSMUSG00000017969 Ptgis ENSCAFG00000011426 PTGIS ENSFCAG00000030511 PTGIS ENSECAG00000016521 PTGIS ENSSSCG00000007463 PTGIS ENSBTAG00000017537 PTGIS ENSCHIG00000011304 PTGIS ENSOARG00000012715 PTGIS ENSCPOG00000034249 PTGIS ENSOANG00000006390 PTGIS ENSCJAG00000000578 PTGIS ENSCATG00000013706 PTGIS ENSMFAG00000033233 PTGIS ENSMMUG00000021692 PTGIS ENSMNEG00000036124 PTGIS ENSPANG00000007535 PTGIS ENSPPAG00000042097 PTGIS ENSPTRG00000013608 PTGIS ENSMICG00000017617 PTGIS ENSCSAG00000015010 PTGIS 108391976 PTGIS ENSRNOG00000008245 AABR07054614.1 ENSMODG00000016298 PTGIS 108700877 ptgis.L ENSXETG00000001780 ptgis ENSACAG00000015827 PTGIS	Compare expression
Sarcopterygii	27 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Cavia porcellus (guinea pig) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Xenopus laevis (African clawed frog) Xenopus tropicalis (western clawed frog) Anolis carolinensis (green anole) Latimeria chalumnae (Coelacanth)	27 genes ENSMUSG00000017969 Ptgis ENSCAFG00000011426 PTGIS ENSFCAG00000030511 PTGIS ENSECAG00000016521 PTGIS ENSSSCG00000007463 PTGIS ENSBTAG00000017537 PTGIS ENSCHIG00000011304 PTGIS ENSOARG00000012715 PTGIS ENSCPOG00000034249 PTGIS ENSOANG00000006390 PTGIS ENSCJAG00000000578 PTGIS ENSCATG00000013706 PTGIS ENSMFAG00000033233 PTGIS ENSMMUG00000021692 PTGIS ENSMNEG00000036124 PTGIS ENSPANG00000007535 PTGIS ENSPPAG00000042097 PTGIS ENSPTRG00000013608 PTGIS ENSMICG00000017617 PTGIS ENSCSAG00000015010 PTGIS 108391976 PTGIS ENSRNOG00000008245 AABR07054614.1 ENSMODG00000016298 PTGIS 108700877 ptgis.L ENSXETG00000001780 ptgis ENSACAG00000015827 PTGIS ENSLACG00000016976 PTGIS	Compare expression
Euteleostomi	40 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Cavia porcellus (guinea pig) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Xenopus laevis (African clawed frog) Xenopus tropicalis (western clawed frog) Anolis carolinensis (green anole) Lepisosteus oculatus (Spotted gar) Anguilla anguilla (European freshwater eel) Astyanax mexicanus (Blind cave fish) Esox lucius (Northern pike) Salmo salar (Atlantic salmon) Gadus morhua (Atlantic cod) Poecilia reticulata (Guppy) Oryzias latipes (Japanese rice fish) Astatotilapia calliptera (Eastern happy) Neolamprologus brichardi (Fairy cichlid) Scophthalmus maximus (Turbot) Gasterosteus aculeatus (Three-spined stickleback) Nothobranchius furzeri (Turquoise killifish) Latimeria chalumnae (Coelacanth)	41 genes ENSMUSG00000017969 Ptgis ENSCAFG00000011426 PTGIS ENSFCAG00000030511 PTGIS ENSECAG00000016521 PTGIS ENSSSCG00000007463 PTGIS ENSBTAG00000017537 PTGIS ENSCHIG00000011304 PTGIS ENSOARG00000012715 PTGIS ENSCPOG00000034249 PTGIS ENSOANG00000006390 PTGIS ENSCJAG00000000578 PTGIS ENSCATG00000013706 PTGIS ENSMFAG00000033233 PTGIS ENSMMUG00000021692 PTGIS ENSMNEG00000036124 PTGIS ENSPANG00000007535 PTGIS ENSPPAG00000042097 PTGIS ENSPTRG00000013608 PTGIS ENSMICG00000017617 PTGIS ENSCSAG00000015010 PTGIS 108391976 PTGIS ENSRNOG00000008245 AABR07054614.1 ENSMODG00000016298 PTGIS 108700877 ptgis.L ENSXETG00000001780 ptgis ENSACAG00000015827 PTGIS ENSLOCG00000003197 ptgis 118211429 LOC118211429 ENSAMXG00000015659 PTGIS ENSELUG00000018290 PTGIS ENSSSAG00000042011 PTGIS ENSSSAG00000080100 thumpd3 ENSGMOG00000007930 PTGIS ENSPREG00000009147 PTGIS ENSORLG00000000653 PTGIS ENSACLG00000023320 PTGIS ENSNBRG00000004899 PTGIS ENSSMAG00000000604 PTGIS ENSGACG00000000936 PTGIS ENSNFUG00015020709 PTGIS ENSLACG00000016976 PTGIS	Compare expression

Showing 1 to 12 of 12 entries

Orthology information comes from OMA : ENSG00000124212.

Paralogs (same species)

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Taxon Name	Gene(s)	Expression comparison	See details
Metazoa	48 genes ENSG00000001630 CYP51A1 ENSG00000019186 CYP24A1 ENSG00000021461 CYP3A43 ENSG00000036530 CYP46A1 ENSG00000059377 TBXAS1 ENSG00000073067 CYP2W1 ENSG00000100197 CYP2D6 ENSG00000106258 CYP3A5 ENSG00000108242 CYP2C18 ENSG00000111012 CYP27B1 ENSG00000130649 CYP2E1 ENSG00000134716 CYP2J2 ENSG00000135929 CYP27A1 ENSG00000138061 CYP1B1 ENSG00000138109 CYP2C9 ENSG00000138115 CYP2C8 ENSG00000140459 CYP11A1 ENSG00000140465 CYP1A1 ENSG00000140505 CYP1A2 ENSG00000142973 CYP4B1 ENSG00000145476 CYP4V2 ENSG00000146233 CYP39A1 ENSG00000148795 CYP17A1 ENSG00000155016 CYP2U1 ENSG00000160868 CYP3A4 ENSG00000160870 CYP3A7 ENSG00000165841 CYP2C19 ENSG00000167600 CYP2S1 ENSG00000167910 CYP7A1 ENSG00000171903 CYP4F11 ENSG00000171954 CYP4F22 ENSG00000172817 CYP7B1 ENSG00000180432 CYP8B1 ENSG00000186104 CYP2R1 ENSG00000186115 CYP4F2 ENSG00000186204 CYP4F12 ENSG00000186377 CYP4X1 ENSG00000186526 CYP4F8 ENSG00000186529 CYP4F3 ENSG00000186684 CYP27C1 ENSG00000197408 CYP2B6 ENSG00000197446 CYP2F1 ENSG00000197838 CYP2A13 ENSG00000205702 CYP2D7 ENSG00000231852 CYP21A2 ENSG00000255974 CYP2A6 ENSG00000276490 AL583836.1 ENSG00000282301 CYP3A7-CYP3A51P	Compare expression: table \| graph