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Gene : HSD17B4 - ENSG00000133835 - Homo sapiens (human)

General information

Expressed in right lobe of thyroid gland and 203 other cell types or tissues.

Gene identifier

ENSG00000133835

Name

HSD17B4

Description

hydroxysteroid 17-beta dehydrogenase 4 [Source:HGNC Symbol;Acc:HGNC:5213]

Organism

Homo sapiens (human)

Synonym(s)

dbp,sdr8c1,mfe-2

Orthologs

40 orthologs

Source data

Retrieve all processed expression values for that gene

Expression graph

80%

Expression table

80%

Reported absence of expression

80%

Orthologs

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Taxon Name	Species with orthologs	Gene(s)	Expression comparison
Catarrhini	3 species Cercocebus atys (Sooty mangabey) Papio anubis (Olive baboon) Chlorocebus sabaeus (Green monkey)	3 genes ENSCATG00000030740 HSD17B4 ENSPANG00000011683 HSD17B4 ENSCSAG00000014659 HSD17B4	Compare expression
Simiiformes	4 species Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Papio anubis (Olive baboon) Chlorocebus sabaeus (Green monkey)	4 genes ENSCJAG00000017062 HSD17B4 ENSCATG00000030740 HSD17B4 ENSPANG00000011683 HSD17B4 ENSCSAG00000014659 HSD17B4	Compare expression
Primates	5 species Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Papio anubis (Olive baboon) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey)	5 genes ENSCJAG00000017062 HSD17B4 ENSCATG00000030740 HSD17B4 ENSPANG00000011683 HSD17B4 ENSMICG00000017025 HSD17B4 ENSCSAG00000014659 HSD17B4	Compare expression
Euarchontoglires	9 species Mus musculus (mouse) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Papio anubis (Olive baboon) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Rattus norvegicus (rat)	9 genes ENSMUSG00000024507 Hsd17b4 ENSOCUG00000010866 HSD17B4 ENSCPOG00000010071 HSD17B4 ENSCJAG00000017062 HSD17B4 ENSCATG00000030740 HSD17B4 ENSPANG00000011683 HSD17B4 ENSMICG00000017025 HSD17B4 ENSCSAG00000014659 HSD17B4 ENSRNOG00000015840 Hsd17b4	Compare expression
Boreoeutheria	17 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Papio anubis (Olive baboon) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat)	17 genes ENSMUSG00000024507 Hsd17b4 ENSCAFG00000000158 HSD17B4 ENSFCAG00000008425 HSD17B4 ENSECAG00000017805 HSD17B4 ENSSSCG00000028431 HSD17B4 ENSBTAG00000006978 HSD17B4 ENSCHIG00000012333 HSD17B4 ENSOARG00000000722 HSD17B4 ENSOCUG00000010866 HSD17B4 ENSCPOG00000010071 HSD17B4 ENSCJAG00000017062 HSD17B4 ENSCATG00000030740 HSD17B4 ENSPANG00000011683 HSD17B4 ENSMICG00000017025 HSD17B4 ENSCSAG00000014659 HSD17B4 108408543 HSD17B4 ENSRNOG00000015840 Hsd17b4	Compare expression
Theria	18 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Papio anubis (Olive baboon) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum)	18 genes ENSMUSG00000024507 Hsd17b4 ENSCAFG00000000158 HSD17B4 ENSFCAG00000008425 HSD17B4 ENSECAG00000017805 HSD17B4 ENSSSCG00000028431 HSD17B4 ENSBTAG00000006978 HSD17B4 ENSCHIG00000012333 HSD17B4 ENSOARG00000000722 HSD17B4 ENSOCUG00000010866 HSD17B4 ENSCPOG00000010071 HSD17B4 ENSCJAG00000017062 HSD17B4 ENSCATG00000030740 HSD17B4 ENSPANG00000011683 HSD17B4 ENSMICG00000017025 HSD17B4 ENSCSAG00000014659 HSD17B4 108408543 HSD17B4 ENSRNOG00000015840 Hsd17b4 ENSMODG00000013536 HSD17B4	Compare expression
Mammalia	19 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Papio anubis (Olive baboon) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum)	19 genes ENSMUSG00000024507 Hsd17b4 ENSCAFG00000000158 HSD17B4 ENSFCAG00000008425 HSD17B4 ENSECAG00000017805 HSD17B4 ENSSSCG00000028431 HSD17B4 ENSBTAG00000006978 HSD17B4 ENSCHIG00000012333 HSD17B4 ENSOARG00000000722 HSD17B4 ENSOCUG00000010866 HSD17B4 ENSCPOG00000010071 HSD17B4 ENSOANG00000002946 HSD17B4 ENSCJAG00000017062 HSD17B4 ENSCATG00000030740 HSD17B4 ENSPANG00000011683 HSD17B4 ENSMICG00000017025 HSD17B4 ENSCSAG00000014659 HSD17B4 108408543 HSD17B4 ENSRNOG00000015840 Hsd17b4 ENSMODG00000013536 HSD17B4	Compare expression
Amniota	22 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Papio anubis (Olive baboon) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Anolis carolinensis (green anole)	22 genes ENSMUSG00000024507 Hsd17b4 ENSCAFG00000000158 HSD17B4 ENSFCAG00000008425 HSD17B4 ENSECAG00000017805 HSD17B4 ENSSSCG00000028431 HSD17B4 ENSBTAG00000006978 HSD17B4 ENSCHIG00000012333 HSD17B4 ENSOARG00000000722 HSD17B4 ENSOCUG00000010866 HSD17B4 ENSCPOG00000010071 HSD17B4 ENSGALG00000002187 HSD17B4 ENSMGAG00000008813 HSD17B4 ENSOANG00000002946 HSD17B4 ENSCJAG00000017062 HSD17B4 ENSCATG00000030740 HSD17B4 ENSPANG00000011683 HSD17B4 ENSMICG00000017025 HSD17B4 ENSCSAG00000014659 HSD17B4 108408543 HSD17B4 ENSRNOG00000015840 Hsd17b4 ENSMODG00000013536 HSD17B4 ENSACAG00000003796 HSD17B4	Compare expression
Tetrapoda	24 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Papio anubis (Olive baboon) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Xenopus laevis (African clawed frog) Xenopus tropicalis (western clawed frog) Anolis carolinensis (green anole)	24 genes ENSMUSG00000024507 Hsd17b4 ENSCAFG00000000158 HSD17B4 ENSFCAG00000008425 HSD17B4 ENSECAG00000017805 HSD17B4 ENSSSCG00000028431 HSD17B4 ENSBTAG00000006978 HSD17B4 ENSCHIG00000012333 HSD17B4 ENSOARG00000000722 HSD17B4 ENSOCUG00000010866 HSD17B4 ENSCPOG00000010071 HSD17B4 ENSGALG00000002187 HSD17B4 ENSMGAG00000008813 HSD17B4 ENSOANG00000002946 HSD17B4 ENSCJAG00000017062 HSD17B4 ENSCATG00000030740 HSD17B4 ENSPANG00000011683 HSD17B4 ENSMICG00000017025 HSD17B4 ENSCSAG00000014659 HSD17B4 108408543 HSD17B4 ENSRNOG00000015840 Hsd17b4 ENSMODG00000013536 HSD17B4 444492 hsd17b4.L ENSXETG00000017534 hsd17b4 ENSACAG00000003796 HSD17B4	Compare expression
Sarcopterygii	25 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Papio anubis (Olive baboon) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Xenopus laevis (African clawed frog) Xenopus tropicalis (western clawed frog) Anolis carolinensis (green anole) Latimeria chalumnae (Coelacanth)	25 genes ENSMUSG00000024507 Hsd17b4 ENSCAFG00000000158 HSD17B4 ENSFCAG00000008425 HSD17B4 ENSECAG00000017805 HSD17B4 ENSSSCG00000028431 HSD17B4 ENSBTAG00000006978 HSD17B4 ENSCHIG00000012333 HSD17B4 ENSOARG00000000722 HSD17B4 ENSOCUG00000010866 HSD17B4 ENSCPOG00000010071 HSD17B4 ENSGALG00000002187 HSD17B4 ENSMGAG00000008813 HSD17B4 ENSOANG00000002946 HSD17B4 ENSCJAG00000017062 HSD17B4 ENSCATG00000030740 HSD17B4 ENSPANG00000011683 HSD17B4 ENSMICG00000017025 HSD17B4 ENSCSAG00000014659 HSD17B4 108408543 HSD17B4 ENSRNOG00000015840 Hsd17b4 ENSMODG00000013536 HSD17B4 444492 hsd17b4.L ENSXETG00000017534 hsd17b4 ENSACAG00000003796 HSD17B4 ENSLACG00000003466 HSD17B4	Compare expression
Euteleostomi	38 species Mus musculus (mouse) Danio rerio (zebrafish) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Papio anubis (Olive baboon) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Xenopus laevis (African clawed frog) Xenopus tropicalis (western clawed frog) Anolis carolinensis (green anole) Lepisosteus oculatus (Spotted gar) Anguilla anguilla (European freshwater eel) Astyanax mexicanus (Blind cave fish) Esox lucius (Northern pike) Salmo salar (Atlantic salmon) Gadus morhua (Atlantic cod) Poecilia reticulata (Guppy) Oryzias latipes (Japanese rice fish) Astatotilapia calliptera (Eastern happy) Neolamprologus brichardi (Fairy cichlid) Scophthalmus maximus (Turbot) Gasterosteus aculeatus (Three-spined stickleback) Latimeria chalumnae (Coelacanth)	38 genes ENSMUSG00000024507 Hsd17b4 ENSDARG00000101239 hsd17b4 ENSCAFG00000000158 HSD17B4 ENSFCAG00000008425 HSD17B4 ENSECAG00000017805 HSD17B4 ENSSSCG00000028431 HSD17B4 ENSBTAG00000006978 HSD17B4 ENSCHIG00000012333 HSD17B4 ENSOARG00000000722 HSD17B4 ENSOCUG00000010866 HSD17B4 ENSCPOG00000010071 HSD17B4 ENSGALG00000002187 HSD17B4 ENSMGAG00000008813 HSD17B4 ENSOANG00000002946 HSD17B4 ENSCJAG00000017062 HSD17B4 ENSCATG00000030740 HSD17B4 ENSPANG00000011683 HSD17B4 ENSMICG00000017025 HSD17B4 ENSCSAG00000014659 HSD17B4 108408543 HSD17B4 ENSRNOG00000015840 Hsd17b4 ENSMODG00000013536 HSD17B4 444492 hsd17b4.L ENSXETG00000017534 hsd17b4 ENSACAG00000003796 HSD17B4 ENSLOCG00000008806 hsd17b4 118206736 hsd17b4 ENSAMXG00000012745 hsd17b4 ENSELUG00000019400 hsd17b4 ENSSSAG00000070946 hsd17b4 ENSGMOG00000007377 hsd17b4 ENSPREG00000014297 hsd17b4 ENSORLG00000003551 hsd17b4 ENSACLG00000013301 hsd17b4 ENSNBRG00000016012 hsd17b4 ENSSMAG00000004707 hsd17b4 ENSGACG00000006242 hsd17b4 ENSLACG00000003466 HSD17B4	Compare expression
Bilateria	40 species Mus musculus (mouse) Danio rerio (zebrafish) Drosophila melanogaster (fruit fly) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Papio anubis (Olive baboon) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Xenopus laevis (African clawed frog) Xenopus tropicalis (western clawed frog) Anolis carolinensis (green anole) Lepisosteus oculatus (Spotted gar) Anguilla anguilla (European freshwater eel) Astyanax mexicanus (Blind cave fish) Esox lucius (Northern pike) Salmo salar (Atlantic salmon) Gadus morhua (Atlantic cod) Poecilia reticulata (Guppy) Oryzias latipes (Japanese rice fish) Astatotilapia calliptera (Eastern happy) Neolamprologus brichardi (Fairy cichlid) Scophthalmus maximus (Turbot) Gasterosteus aculeatus (Three-spined stickleback) Latimeria chalumnae (Coelacanth) Drosophila pseudoobscura ()	40 genes ENSMUSG00000024507 Hsd17b4 ENSDARG00000101239 hsd17b4 FBgn0030731 Mfe2 ENSCAFG00000000158 HSD17B4 ENSFCAG00000008425 HSD17B4 ENSECAG00000017805 HSD17B4 ENSSSCG00000028431 HSD17B4 ENSBTAG00000006978 HSD17B4 ENSCHIG00000012333 HSD17B4 ENSOARG00000000722 HSD17B4 ENSOCUG00000010866 HSD17B4 ENSCPOG00000010071 HSD17B4 ENSGALG00000002187 HSD17B4 ENSMGAG00000008813 HSD17B4 ENSOANG00000002946 HSD17B4 ENSCJAG00000017062 HSD17B4 ENSCATG00000030740 HSD17B4 ENSPANG00000011683 HSD17B4 ENSMICG00000017025 HSD17B4 ENSCSAG00000014659 HSD17B4 108408543 HSD17B4 ENSRNOG00000015840 Hsd17b4 ENSMODG00000013536 HSD17B4 444492 hsd17b4.L ENSXETG00000017534 hsd17b4 ENSACAG00000003796 HSD17B4 ENSLOCG00000008806 hsd17b4 118206736 hsd17b4 ENSAMXG00000012745 hsd17b4 ENSELUG00000019400 hsd17b4 ENSSSAG00000070946 hsd17b4 ENSGMOG00000007377 hsd17b4 ENSPREG00000014297 hsd17b4 ENSORLG00000003551 hsd17b4 ENSACLG00000013301 hsd17b4 ENSNBRG00000016012 hsd17b4 ENSSMAG00000004707 hsd17b4 ENSGACG00000006242 hsd17b4 ENSLACG00000003466 HSD17B4 FBgn0077449 Dpse\GA17436	Compare expression

Showing 1 to 12 of 12 entries

Orthology information comes from OMA : ENSG00000133835.

Cross-references

CCDS

CCDS4126 (CCDS4126.1),CCDS56378 (CCDS56378.1),CCDS56379 (CCDS56379.1)

Ensembl

ENSG00000133835 (HSD17B4)

HGNC

HGNC:5213 (HSD17B4)

EMBL

AC010409,AC024564,AF057720,AF057721,AF057722,AF057723,AF057724,AF057725

GeneCards

ENSG00000133835

UniProtKB/Swiss-Prot

DHB4_HUMAN,P51659

UniProtKB/TrEMBL

A0A2R8Y674,A0A2R8Y674_HUMAN,A0A2R8Y7L2,A0A2R8Y7L2_HUMAN,A0A2R8Y7W2,A0A2R8Y7W2_HUMAN,A0A2R8YCN2,A0A2R8YCN2_HUMAN