Search Genes

Gene : GRM5 - ENSG00000168959 - Homo sapiens (human)

General information

Expressed in endothelial cell and 74 other cell types or tissues.

Gene identifier

ENSG00000168959

Name

GRM5

Description

glutamate metabotropic receptor 5 [Source:HGNC Symbol;Acc:HGNC:4597]

Organism

Homo sapiens (human)

Synonym(s)

mglu5,ppp1r86,mglur5,gprc1e

Orthologs

45 orthologs

Paralogs

7 paralogs

Source data

Retrieve all processed expression values for that gene

Expression graph

80%

Expression table

80%

Reported absence of expression

80%

Orthologs

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Taxon Name	Species with orthologs	Gene(s)	Expression comparison
Homininae	3 species Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee)	3 genes ENSGGOG00000008825 GRM5 ENSPPAG00000028715 GRM5 ENSPTRG00000004153 GRM5	Compare expression
Catarrhini	8 species Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee)	8 genes ENSCATG00000039645 GRM5 ENSMFAG00000034520 GRM5 ENSMMUG00000010184 GRM5 ENSMNEG00000034358 GRM5 ENSPANG00000010013 GRM5 ENSGGOG00000008825 GRM5 ENSPPAG00000028715 GRM5 ENSPTRG00000004153 GRM5	Compare expression
Simiiformes	9 species Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee)	9 genes ENSCJAG00000000695 GRM5 ENSCATG00000039645 GRM5 ENSMFAG00000034520 GRM5 ENSMMUG00000010184 GRM5 ENSMNEG00000034358 GRM5 ENSPANG00000010013 GRM5 ENSGGOG00000008825 GRM5 ENSPPAG00000028715 GRM5 ENSPTRG00000004153 GRM5	Compare expression
Primates	10 species Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur)	10 genes ENSCJAG00000000695 GRM5 ENSCATG00000039645 GRM5 ENSMFAG00000034520 GRM5 ENSMMUG00000010184 GRM5 ENSMNEG00000034358 GRM5 ENSPANG00000010013 GRM5 ENSGGOG00000008825 GRM5 ENSPPAG00000028715 GRM5 ENSPTRG00000004153 GRM5 ENSMICG00000002451 GRM5	Compare expression
Euarchontoglires	14 species Mus musculus (mouse) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Rattus norvegicus (rat)	14 genes ENSMUSG00000049583 Grm5 ENSOCUG00000012817 GRM5 ENSCPOG00000009056 GRM5 ENSCJAG00000000695 GRM5 ENSCATG00000039645 GRM5 ENSMFAG00000034520 GRM5 ENSMMUG00000010184 GRM5 ENSMNEG00000034358 GRM5 ENSPANG00000010013 GRM5 ENSGGOG00000008825 GRM5 ENSPPAG00000028715 GRM5 ENSPTRG00000004153 GRM5 ENSMICG00000002451 GRM5 ENSRNOG00000016429 Grm5	Compare expression
Boreoeutheria	19 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Manis javanica (Malayan pangolin) Rattus norvegicus (rat)	19 genes ENSMUSG00000049583 Grm5 ENSCAFG00000004381 GRM5 ENSFCAG00000035511 GRM5 ENSECAG00000018967 GRM5 ENSSSCG00000029865 GRM5 ENSOCUG00000012817 GRM5 ENSCPOG00000009056 GRM5 ENSCJAG00000000695 GRM5 ENSCATG00000039645 GRM5 ENSMFAG00000034520 GRM5 ENSMMUG00000010184 GRM5 ENSMNEG00000034358 GRM5 ENSPANG00000010013 GRM5 ENSGGOG00000008825 GRM5 ENSPPAG00000028715 GRM5 ENSPTRG00000004153 GRM5 ENSMICG00000002451 GRM5 108386876 GRM5 ENSRNOG00000016429 Grm5	Compare expression
Theria	20 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum)	20 genes ENSMUSG00000049583 Grm5 ENSCAFG00000004381 GRM5 ENSFCAG00000035511 GRM5 ENSECAG00000018967 GRM5 ENSSSCG00000029865 GRM5 ENSOCUG00000012817 GRM5 ENSCPOG00000009056 GRM5 ENSCJAG00000000695 GRM5 ENSCATG00000039645 GRM5 ENSMFAG00000034520 GRM5 ENSMMUG00000010184 GRM5 ENSMNEG00000034358 GRM5 ENSPANG00000010013 GRM5 ENSGGOG00000008825 GRM5 ENSPPAG00000028715 GRM5 ENSPTRG00000004153 GRM5 ENSMICG00000002451 GRM5 108386876 GRM5 ENSRNOG00000016429 Grm5 ENSMODG00000002773 GRM5	Compare expression
Mammalia	21 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum)	21 genes ENSMUSG00000049583 Grm5 ENSCAFG00000004381 GRM5 ENSFCAG00000035511 GRM5 ENSECAG00000018967 GRM5 ENSSSCG00000029865 GRM5 ENSOCUG00000012817 GRM5 ENSCPOG00000009056 GRM5 ENSOANG00000008870 GRM5 ENSCJAG00000000695 GRM5 ENSCATG00000039645 GRM5 ENSMFAG00000034520 GRM5 ENSMMUG00000010184 GRM5 ENSMNEG00000034358 GRM5 ENSPANG00000010013 GRM5 ENSGGOG00000008825 GRM5 ENSPPAG00000028715 GRM5 ENSPTRG00000004153 GRM5 ENSMICG00000002451 GRM5 108386876 GRM5 ENSRNOG00000016429 Grm5 ENSMODG00000002773 GRM5	Compare expression
Amniota	24 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Anolis carolinensis (green anole)	24 genes ENSMUSG00000049583 Grm5 ENSCAFG00000004381 GRM5 ENSFCAG00000035511 GRM5 ENSECAG00000018967 GRM5 ENSSSCG00000029865 GRM5 ENSOCUG00000012817 GRM5 ENSCPOG00000009056 GRM5 ENSGALG00000017238 GRM5 ENSMGAG00000015221 GRM5 ENSOANG00000008870 GRM5 ENSCJAG00000000695 GRM5 ENSCATG00000039645 GRM5 ENSMFAG00000034520 GRM5 ENSMMUG00000010184 GRM5 ENSMNEG00000034358 GRM5 ENSPANG00000010013 GRM5 ENSGGOG00000008825 GRM5 ENSPPAG00000028715 GRM5 ENSPTRG00000004153 GRM5 ENSMICG00000002451 GRM5 108386876 GRM5 ENSRNOG00000016429 Grm5 ENSMODG00000002773 GRM5 ENSACAG00000015032 GRM5	Compare expression
Tetrapoda	26 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Xenopus laevis (African clawed frog) Xenopus tropicalis (western clawed frog) Anolis carolinensis (green anole)	27 genes ENSMUSG00000049583 Grm5 ENSCAFG00000004381 GRM5 ENSFCAG00000035511 GRM5 ENSECAG00000018967 GRM5 ENSSSCG00000029865 GRM5 ENSOCUG00000012817 GRM5 ENSCPOG00000009056 GRM5 ENSGALG00000017238 GRM5 ENSMGAG00000015221 GRM5 ENSOANG00000008870 GRM5 ENSCJAG00000000695 GRM5 ENSCATG00000039645 GRM5 ENSMFAG00000034520 GRM5 ENSMMUG00000010184 GRM5 ENSMNEG00000034358 GRM5 ENSPANG00000010013 GRM5 ENSGGOG00000008825 GRM5 ENSPPAG00000028715 GRM5 ENSPTRG00000004153 GRM5 ENSMICG00000002451 GRM5 108386876 GRM5 ENSRNOG00000016429 Grm5 ENSMODG00000002773 GRM5 108707585 LOC108707585 108710022 LOC108710022 ENSXETG00000011740 grm5 ENSACAG00000015032 GRM5	Compare expression
Euteleostomi	39 species Mus musculus (mouse) Danio rerio (zebrafish) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Xenopus laevis (African clawed frog) Xenopus tropicalis (western clawed frog) Anolis carolinensis (green anole) Lepisosteus oculatus (Spotted gar) Anguilla anguilla (European freshwater eel) Astyanax mexicanus (Blind cave fish) Esox lucius (Northern pike) Salmo salar (Atlantic salmon) Gadus morhua (Atlantic cod) Poecilia reticulata (Guppy) Oryzias latipes (Japanese rice fish) Astatotilapia calliptera (Eastern happy) Neolamprologus brichardi (Fairy cichlid) Scophthalmus maximus (Turbot) Gasterosteus aculeatus (Three-spined stickleback)	41 genes ENSMUSG00000049583 Grm5 ENSDARG00000102067 grm5b ENSCAFG00000004381 GRM5 ENSFCAG00000035511 GRM5 ENSECAG00000018967 GRM5 ENSSSCG00000029865 GRM5 ENSOCUG00000012817 GRM5 ENSCPOG00000009056 GRM5 ENSGALG00000017238 GRM5 ENSMGAG00000015221 GRM5 ENSOANG00000008870 GRM5 ENSCJAG00000000695 GRM5 ENSCATG00000039645 GRM5 ENSMFAG00000034520 GRM5 ENSMMUG00000010184 GRM5 ENSMNEG00000034358 GRM5 ENSPANG00000010013 GRM5 ENSGGOG00000008825 GRM5 ENSPPAG00000028715 GRM5 ENSPTRG00000004153 GRM5 ENSMICG00000002451 GRM5 108386876 GRM5 ENSRNOG00000016429 Grm5 ENSMODG00000002773 GRM5 108707585 LOC108707585 108710022 LOC108710022 ENSXETG00000011740 grm5 ENSACAG00000015032 GRM5 ENSLOCG00000007164 grm5b 118208818 grm5b ENSAMXG00000003924 grm5b ENSELUG00000000414 grm5b ENSSSAG00000051457 grm5b ENSSSAG00000065084 grm5b ENSGMOG00000004428 grm5b ENSPREG00000020546 grm5b ENSORLG00000010875 grm5b ENSACLG00000023565 grm5b ENSNBRG00000014746 grm5b ENSSMAG00000019258 grm5b ENSGACG00000007968 grm5b	Compare expression
Chordata	40 species Mus musculus (mouse) Danio rerio (zebrafish) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Xenopus laevis (African clawed frog) Xenopus tropicalis (western clawed frog) Anolis carolinensis (green anole) Lepisosteus oculatus (Spotted gar) Anguilla anguilla (European freshwater eel) Astyanax mexicanus (Blind cave fish) Esox lucius (Northern pike) Salmo salar (Atlantic salmon) Gadus morhua (Atlantic cod) Poecilia reticulata (Guppy) Oryzias latipes (Japanese rice fish) Astatotilapia calliptera (Eastern happy) Neolamprologus brichardi (Fairy cichlid) Scophthalmus maximus (Turbot) Gasterosteus aculeatus (Three-spined stickleback) Branchiostoma lanceolatum (Common lancelet)	45 genes ENSMUSG00000049583 Grm5 ENSDARG00000102067 grm5b ENSCAFG00000004381 GRM5 ENSFCAG00000035511 GRM5 ENSECAG00000018967 GRM5 ENSSSCG00000029865 GRM5 ENSOCUG00000012817 GRM5 ENSCPOG00000009056 GRM5 ENSGALG00000017238 GRM5 ENSMGAG00000015221 GRM5 ENSOANG00000008870 GRM5 ENSCJAG00000000695 GRM5 ENSCATG00000039645 GRM5 ENSMFAG00000034520 GRM5 ENSMMUG00000010184 GRM5 ENSMNEG00000034358 GRM5 ENSPANG00000010013 GRM5 ENSGGOG00000008825 GRM5 ENSPPAG00000028715 GRM5 ENSPTRG00000004153 GRM5 ENSMICG00000002451 GRM5 108386876 GRM5 ENSRNOG00000016429 Grm5 ENSMODG00000002773 GRM5 108707585 LOC108707585 108710022 LOC108710022 ENSXETG00000011740 grm5 ENSACAG00000015032 GRM5 ENSLOCG00000007164 grm5b 118208818 grm5b ENSAMXG00000003924 grm5b ENSELUG00000000414 grm5b ENSSSAG00000051457 grm5b ENSSSAG00000065084 grm5b ENSGMOG00000004428 grm5b ENSPREG00000020546 grm5b ENSORLG00000010875 grm5b ENSACLG00000023565 grm5b ENSNBRG00000014746 grm5b ENSSMAG00000019258 grm5b ENSGACG00000007968 grm5b BL07255 GRM3 BL14485 GRM3 BL15226 GRM3 BL95582 GRM8	Compare expression

Showing 1 to 12 of 12 entries

Orthology information comes from OMA : ENSG00000168959.

Paralogs (same species)

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Taxon Name	Gene(s)	Expression comparison	See details
Vertebrata	7 genes ENSG00000113262 GRM6 ENSG00000124493 GRM4 ENSG00000152822 GRM1 ENSG00000164082 GRM2 ENSG00000179603 GRM8 ENSG00000196277 GRM7 ENSG00000198822 GRM3	Compare expression: table \| graph

Showing 1 to 1 of 1 entries

Paralogy information comes from OMA : ENSG00000168959.

Cross-references

CCDS

CCDS44694 (CCDS44694.1),CCDS8283 (CCDS8283.1)

Ensembl

ENSG00000168959 (GRM5)

HGNC

HGNC:4597 (GRM5)

EMBL

AP000626,AP001482,AP001828,AP003120,AP006214,AP006215,AY608336,D28538

GeneCards

ENSG00000168959

UniProtKB/Swiss-Prot

GRM5_HUMAN,P41594

UniProtKB/TrEMBL

A8MT20,A8MT20_HUMAN,H7C223,H7C223_HUMAN