Search Genes

Gene : - ENSOARG00000008628 - Ovis aries (Sheep)

General information

Expressed in ileum and 55 other cell types or tissues.

Gene identifier

ENSOARG00000008628

Name

Description

DNA topoisomerase I

Organism

Ovis aries (Sheep)

Synonym(s)

ENSOARP00000009259,ENSOART00000009395

Orthologs

45 orthologs

Paralogs

2 paralogs

Source data

Retrieve all processed expression values for that gene

Expression graph

80%

Expression table

80%

Reported absence of expression

80%

Orthologs

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Taxon Name	Species with orthologs	Gene(s)	Expression comparison
Laurasiatheria	4 species Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Manis javanica (Malayan pangolin)	4 genes ENSCAFG00000009058 TOP1 ENSFCAG00000009029 TOP1 ENSECAG00000000383 TOP1 108407251 TOP1	Compare expression
Boreoeutheria	20 species Homo sapiens (human) Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat)	20 genes ENSG00000198900 TOP1 ENSMUSG00000070544 Top1 ENSCAFG00000009058 TOP1 ENSFCAG00000009029 TOP1 ENSECAG00000000383 TOP1 ENSOCUG00000008221 TOP1 ENSCPOG00000009076 TOP1 ENSCJAG00000018101 TOP1 ENSCATG00000044132 TOP1 ENSMFAG00000042654 TOP1 ENSMMUG00000011112 TOP1 ENSMNEG00000039142 TOP1 ENSPANG00000025552 TOP1 ENSGGOG00000009000 TOP1 ENSPPAG00000043186 TOP1 ENSPTRG00000013498 TOP1 ENSMICG00000007082 TOP1 ENSCSAG00000013942 TOP1 108407251 TOP1 ENSRNOG00000047611 Top1	Compare expression
Theria	21 species Homo sapiens (human) Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum)	21 genes ENSG00000198900 TOP1 ENSMUSG00000070544 Top1 ENSCAFG00000009058 TOP1 ENSFCAG00000009029 TOP1 ENSECAG00000000383 TOP1 ENSOCUG00000008221 TOP1 ENSCPOG00000009076 TOP1 ENSCJAG00000018101 TOP1 ENSCATG00000044132 TOP1 ENSMFAG00000042654 TOP1 ENSMMUG00000011112 TOP1 ENSMNEG00000039142 TOP1 ENSPANG00000025552 TOP1 ENSGGOG00000009000 TOP1 ENSPPAG00000043186 TOP1 ENSPTRG00000013498 TOP1 ENSMICG00000007082 TOP1 ENSCSAG00000013942 TOP1 108407251 TOP1 ENSRNOG00000047611 Top1 ENSMODG00000000573 TOP1	Compare expression
Mammalia	22 species Homo sapiens (human) Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum)	22 genes ENSG00000198900 TOP1 ENSMUSG00000070544 Top1 ENSCAFG00000009058 TOP1 ENSFCAG00000009029 TOP1 ENSECAG00000000383 TOP1 ENSOCUG00000008221 TOP1 ENSCPOG00000009076 TOP1 ENSOANG00000014354 TOP1 ENSCJAG00000018101 TOP1 ENSCATG00000044132 TOP1 ENSMFAG00000042654 TOP1 ENSMMUG00000011112 TOP1 ENSMNEG00000039142 TOP1 ENSPANG00000025552 TOP1 ENSGGOG00000009000 TOP1 ENSPPAG00000043186 TOP1 ENSPTRG00000013498 TOP1 ENSMICG00000007082 TOP1 ENSCSAG00000013942 TOP1 108407251 TOP1 ENSRNOG00000047611 Top1 ENSMODG00000000573 TOP1	Compare expression
Amniota	25 species Homo sapiens (human) Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Anolis carolinensis (green anole)	25 genes ENSG00000198900 TOP1 ENSMUSG00000070544 Top1 ENSCAFG00000009058 TOP1 ENSFCAG00000009029 TOP1 ENSECAG00000000383 TOP1 ENSOCUG00000008221 TOP1 ENSCPOG00000009076 TOP1 ENSGALG00000003681 TOP1 ENSMGAG00000003320 TOP1 ENSOANG00000014354 TOP1 ENSCJAG00000018101 TOP1 ENSCATG00000044132 TOP1 ENSMFAG00000042654 TOP1 ENSMMUG00000011112 TOP1 ENSMNEG00000039142 TOP1 ENSPANG00000025552 TOP1 ENSGGOG00000009000 TOP1 ENSPPAG00000043186 TOP1 ENSPTRG00000013498 TOP1 ENSMICG00000007082 TOP1 ENSCSAG00000013942 TOP1 108407251 TOP1 ENSRNOG00000047611 Top1 ENSMODG00000000573 TOP1 ENSACAG00000010889 TOP1	Compare expression
Tetrapoda	27 species Homo sapiens (human) Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Xenopus laevis (African clawed frog) Xenopus tropicalis (western clawed frog) Anolis carolinensis (green anole)	27 genes ENSG00000198900 TOP1 ENSMUSG00000070544 Top1 ENSCAFG00000009058 TOP1 ENSFCAG00000009029 TOP1 ENSECAG00000000383 TOP1 ENSOCUG00000008221 TOP1 ENSCPOG00000009076 TOP1 ENSGALG00000003681 TOP1 ENSMGAG00000003320 TOP1 ENSOANG00000014354 TOP1 ENSCJAG00000018101 TOP1 ENSCATG00000044132 TOP1 ENSMFAG00000042654 TOP1 ENSMMUG00000011112 TOP1 ENSMNEG00000039142 TOP1 ENSPANG00000025552 TOP1 ENSGGOG00000009000 TOP1 ENSPPAG00000043186 TOP1 ENSPTRG00000013498 TOP1 ENSMICG00000007082 TOP1 ENSCSAG00000013942 TOP1 108407251 TOP1 ENSRNOG00000047611 Top1 ENSMODG00000000573 TOP1 399263 top1 ENSXETG00000040254 top1.1 ENSACAG00000010889 TOP1	Compare expression
Sarcopterygii	28 species Homo sapiens (human) Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Xenopus laevis (African clawed frog) Xenopus tropicalis (western clawed frog) Anolis carolinensis (green anole) Latimeria chalumnae (Coelacanth)	28 genes ENSG00000198900 TOP1 ENSMUSG00000070544 Top1 ENSCAFG00000009058 TOP1 ENSFCAG00000009029 TOP1 ENSECAG00000000383 TOP1 ENSOCUG00000008221 TOP1 ENSCPOG00000009076 TOP1 ENSGALG00000003681 TOP1 ENSMGAG00000003320 TOP1 ENSOANG00000014354 TOP1 ENSCJAG00000018101 TOP1 ENSCATG00000044132 TOP1 ENSMFAG00000042654 TOP1 ENSMMUG00000011112 TOP1 ENSMNEG00000039142 TOP1 ENSPANG00000025552 TOP1 ENSGGOG00000009000 TOP1 ENSPPAG00000043186 TOP1 ENSPTRG00000013498 TOP1 ENSMICG00000007082 TOP1 ENSCSAG00000013942 TOP1 108407251 TOP1 ENSRNOG00000047611 Top1 ENSMODG00000000573 TOP1 399263 top1 ENSXETG00000040254 top1.1 ENSACAG00000010889 TOP1 ENSLACG00000018184 TOP1	Compare expression
Euteleostomi	41 species Homo sapiens (human) Mus musculus (mouse) Danio rerio (zebrafish) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Xenopus laevis (African clawed frog) Xenopus tropicalis (western clawed frog) Anolis carolinensis (green anole) Lepisosteus oculatus (Spotted gar) Anguilla anguilla (European freshwater eel) Esox lucius (Northern pike) Salmo salar (Atlantic salmon) Gadus morhua (Atlantic cod) Poecilia reticulata (Guppy) Oryzias latipes (Japanese rice fish) Astatotilapia calliptera (Eastern happy) Neolamprologus brichardi (Fairy cichlid) Scophthalmus maximus (Turbot) Gasterosteus aculeatus (Three-spined stickleback) Nothobranchius furzeri (Turquoise killifish) Latimeria chalumnae (Coelacanth)	43 genes ENSG00000198900 TOP1 ENSMUSG00000070544 Top1 ENSDARG00000070545 top1l ENSCAFG00000009058 TOP1 ENSFCAG00000009029 TOP1 ENSECAG00000000383 TOP1 ENSOCUG00000008221 TOP1 ENSCPOG00000009076 TOP1 ENSGALG00000003681 TOP1 ENSMGAG00000003320 TOP1 ENSOANG00000014354 TOP1 ENSCJAG00000018101 TOP1 ENSCATG00000044132 TOP1 ENSMFAG00000042654 TOP1 ENSMMUG00000011112 TOP1 ENSMNEG00000039142 TOP1 ENSPANG00000025552 TOP1 ENSGGOG00000009000 TOP1 ENSPPAG00000043186 TOP1 ENSPTRG00000013498 TOP1 ENSMICG00000007082 TOP1 ENSCSAG00000013942 TOP1 108407251 TOP1 ENSRNOG00000047611 Top1 ENSMODG00000000573 TOP1 399263 top1 ENSXETG00000040254 top1.1 ENSACAG00000010889 TOP1 ENSLOCG00000004545 top1 118208219 top1 118210661 top1l ENSELUG00000004758 top1l ENSSSAG00000006599 top1l ENSSSAG00000081414 top1l ENSGMOG00000017862 top1l ENSPREG00000022283 top1l ENSORLG00000013917 top1l ENSACLG00000020954 top1l ENSNBRG00000023138 top1l ENSSMAG00000013729 top1l ENSGACG00000010175 top1l ENSNFUG00015015254 TOP1L ENSLACG00000018184 TOP1	Compare expression
Chordata	42 species Homo sapiens (human) Mus musculus (mouse) Danio rerio (zebrafish) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Xenopus laevis (African clawed frog) Xenopus tropicalis (western clawed frog) Anolis carolinensis (green anole) Lepisosteus oculatus (Spotted gar) Anguilla anguilla (European freshwater eel) Esox lucius (Northern pike) Salmo salar (Atlantic salmon) Gadus morhua (Atlantic cod) Poecilia reticulata (Guppy) Oryzias latipes (Japanese rice fish) Astatotilapia calliptera (Eastern happy) Neolamprologus brichardi (Fairy cichlid) Scophthalmus maximus (Turbot) Gasterosteus aculeatus (Three-spined stickleback) Nothobranchius furzeri (Turquoise killifish) Branchiostoma lanceolatum (Common lancelet) Latimeria chalumnae (Coelacanth)	44 genes ENSG00000198900 TOP1 ENSMUSG00000070544 Top1 ENSDARG00000070545 top1l ENSCAFG00000009058 TOP1 ENSFCAG00000009029 TOP1 ENSECAG00000000383 TOP1 ENSOCUG00000008221 TOP1 ENSCPOG00000009076 TOP1 ENSGALG00000003681 TOP1 ENSMGAG00000003320 TOP1 ENSOANG00000014354 TOP1 ENSCJAG00000018101 TOP1 ENSCATG00000044132 TOP1 ENSMFAG00000042654 TOP1 ENSMMUG00000011112 TOP1 ENSMNEG00000039142 TOP1 ENSPANG00000025552 TOP1 ENSGGOG00000009000 TOP1 ENSPPAG00000043186 TOP1 ENSPTRG00000013498 TOP1 ENSMICG00000007082 TOP1 ENSCSAG00000013942 TOP1 108407251 TOP1 ENSRNOG00000047611 Top1 ENSMODG00000000573 TOP1 399263 top1 ENSXETG00000040254 top1.1 ENSACAG00000010889 TOP1 ENSLOCG00000004545 top1 118208219 top1 118210661 top1l ENSELUG00000004758 top1l ENSSSAG00000006599 top1l ENSSSAG00000081414 top1l ENSGMOG00000017862 top1l ENSPREG00000022283 top1l ENSORLG00000013917 top1l ENSACLG00000020954 top1l ENSNBRG00000023138 top1l ENSSMAG00000013729 top1l ENSGACG00000010175 top1l ENSNFUG00015015254 TOP1L BL15029 TOP1 ENSLACG00000018184 TOP1	Compare expression
Bilateria	43 species Homo sapiens (human) Mus musculus (mouse) Danio rerio (zebrafish) Caenorhabditis elegans (nematode) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Xenopus laevis (African clawed frog) Xenopus tropicalis (western clawed frog) Anolis carolinensis (green anole) Lepisosteus oculatus (Spotted gar) Anguilla anguilla (European freshwater eel) Esox lucius (Northern pike) Salmo salar (Atlantic salmon) Gadus morhua (Atlantic cod) Poecilia reticulata (Guppy) Oryzias latipes (Japanese rice fish) Astatotilapia calliptera (Eastern happy) Neolamprologus brichardi (Fairy cichlid) Scophthalmus maximus (Turbot) Gasterosteus aculeatus (Three-spined stickleback) Nothobranchius furzeri (Turquoise killifish) Branchiostoma lanceolatum (Common lancelet) Latimeria chalumnae (Coelacanth)	45 genes ENSG00000198900 TOP1 ENSMUSG00000070544 Top1 ENSDARG00000070545 top1l WBGene00006595 top-1 ENSCAFG00000009058 TOP1 ENSFCAG00000009029 TOP1 ENSECAG00000000383 TOP1 ENSOCUG00000008221 TOP1 ENSCPOG00000009076 TOP1 ENSGALG00000003681 TOP1 ENSMGAG00000003320 TOP1 ENSOANG00000014354 TOP1 ENSCJAG00000018101 TOP1 ENSCATG00000044132 TOP1 ENSMFAG00000042654 TOP1 ENSMMUG00000011112 TOP1 ENSMNEG00000039142 TOP1 ENSPANG00000025552 TOP1 ENSGGOG00000009000 TOP1 ENSPPAG00000043186 TOP1 ENSPTRG00000013498 TOP1 ENSMICG00000007082 TOP1 ENSCSAG00000013942 TOP1 108407251 TOP1 ENSRNOG00000047611 Top1 ENSMODG00000000573 TOP1 399263 top1 ENSXETG00000040254 top1.1 ENSACAG00000010889 TOP1 ENSLOCG00000004545 top1 118208219 top1 118210661 top1l ENSELUG00000004758 top1l ENSSSAG00000006599 top1l ENSSSAG00000081414 top1l ENSGMOG00000017862 top1l ENSPREG00000022283 top1l ENSORLG00000013917 top1l ENSACLG00000020954 top1l ENSNBRG00000023138 top1l ENSSMAG00000013729 top1l ENSGACG00000010175 top1l ENSNFUG00015015254 TOP1L BL15029 TOP1 ENSLACG00000018184 TOP1	Compare expression

Showing 1 to 10 of 10 entries

Orthology information comes from OMA : ENSOARG00000008628.

Paralogs (same species)

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Taxon Name	Gene(s)	Expression comparison	See details
Artiodactyla	1 gene ENSOARG00000001406 TOP1	Compare expression: table \| graph
Opisthokonta	2 genes ENSOARG00000001251 TOP1MT ENSOARG00000001406 TOP1	Compare expression: table \| graph

Showing 1 to 2 of 2 entries

Paralogy information comes from OMA : ENSOARG00000008628.

Cross-references

Ensembl

ENSOARG00000008628,ENSOARP00000009259,ENSOART00000009395

EMBL

AMGL01071526

UniProtKB/TrEMBL

W5PFP4,W5PFP4_SHEEP